Kelo Cote vs Mederma 2019 | What’s Better for Scars?

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Kelo Cote vs Mederma

Kelo-Cote vs Mederma

Preview
Best Value for Money
Kelo-cote Advanced Formula Scar Gel 60g
Best Budget Option
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Editor's Top Pick
NewGel+ Advanced Silicone Gel for Scars, 1 Ounce
Product Name
KELO-COTE Scar Gel
Mederma Advanced Scar Gel
NewGel+ Advanced Silicone Gel for Scars
Product Size
60 g
50 g
30 g
Recommended for Scars?
Active Ingredients
Polysiloxanes (Silicone), Silicon Dioxide
Cepalin® (Onion Extract Gel)
Polymerized Siloxanes (Silicone), Vitamin E
Application Frequency
2x Daily
1x Daily
2x Daily
Customer Rating
Prime Eligibility
Price
$59.50
$28.80
$54.00
Best Value for Money
Preview
Kelo-cote Advanced Formula Scar Gel 60g
Product Name
KELO-COTE Scar Gel
Product Size
60 g
Recommended for Scars?
Active Ingredients
Polysiloxanes (Silicone), Silicon Dioxide
Application Frequency
2x Daily
Customer Rating
Prime Eligibility
Price
$59.50
More Information
Best Budget Option
Preview
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Product Name
Mederma Advanced Scar Gel
Product Size
50 g
Recommended for Scars?
Active Ingredients
Cepalin® (Onion Extract Gel)
Application Frequency
1x Daily
Customer Rating
Prime Eligibility
Price
$28.80
More Information
Editor's Top Pick
Preview
NewGel+ Advanced Silicone Gel for Scars, 1 Ounce
Product Name
NewGel+ Advanced Silicone Gel for Scars
Product Size
30 g
Recommended for Scars?
Active Ingredients
Polymerized Siloxanes (Silicone), Vitamin E
Application Frequency
2x Daily
Customer Rating
Prime Eligibility
Price
$54.00
More Information

Last Updated: 2020-04-05 / Images from Amazon PA API

Our Recommendations

If you want the best results, go for a silicone gel like Kelo-Cote.

Silicone gels are recommended by the International Advisory Panel on Scar Management for both hypertrophic scars and keloids. (1)

I like silicone gels because they’re very effective, lightweight, and dry quickly.

On the other hand, if you’re on a limited budget, a good alternative is Mederma.

This popular scar gel can provide you excellent results without breaking the bank.

The downside, however, is that the clinical evidence is not yet conclusive. (1)

RELATED:

Kelo-Cote Advanced Scar Gel

PROS

  • Flattens existing scars
  • Reduces discoloration
  • Excellent reviews

CONS

  • Results require patience
  • More expensive

About Kelo-Cote

Kelo-Cote is an excellent silicone gel that contains: 

  • Polysiloxanes (Silicone Gel)
  • Silicon Dioxide (Protective Layer)

Silicone gel helps reduce scar height and size by preventing collagen overproduction (a major contributor in the formation of hypertrophic scars and keloids).

This creates an ideal environment for your body to replace the scar tissue with normal-looking skin (i.e. collagen remodeling).

Kelo-Cote also contains silicon dioxide to add a layer of protection around the scar to promote optimal wound healing.

Kelo-Cote is thin, clear, and odorless, which makes it easy to apply and leave on your skin.

Key Features

  • Medical grade silicone gel
  • Invisible, odorless, fast drying
  • Comes in 15g and 60g versions

Key Benefits

  • Flattens existing scars (surgery, trauma, C-section, burns, acne, etc.)
  • Prevents new scars
  • Reduces discoloration (redness)

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Silicone?

The International Advisory Panel on Scar Management recommends silicone gels and sheets as first-line treatment for hypertrophic scars and keloids. (1)

Researchers believe silicone products work by hydrating and protecting the scar. This prevents skin dehydration which may contribute to abnormal scar formation. (2)

Silicone gels are best for scars on your face, hands, and other noticeable areas of your body. That’s because silicone gels are invisible once applied and dry fairly quickly.

You should apply silicone gels twice a day for at least 2 months.

Kelo-Cote Reviews

Reviews of Kelo-Cote on Amazon are mainly positive. Many reviewers noticed improvements in post-surgical scars, hypertrophic scars, and keloids.

Among the negative reviews, some people felt that Kelo-Cote didn’t deliver any better results than Vaseline or Mederma.

As with all skincare products, your mileage may vary (YMMV).

The Bottom-Line

Kelo-Cote Advanced Scar Gel is an excellent choice for hypertrophic scars and keloids.

Mederma Advanced Scar Gel

PROS

  • Softens existing scars
  • Reduces discoloration
  • Thousands of reviews
  • Affordable

CONS

  • Inconclusive clinical studies
  • Results require patience
  • May cause itchiness, irritation, or redness

About Mederma

If you want great results that won’t break the bank, Mederma is an excellent option.

Featuring Cepalin (onion extract), Mederma has been the #1 pharmacist recommended brand for 15 years.

Although clinical studies of onion extract are somewhat mixed, it’s clear that Mederma has helped thousands of people with their scar problems.

Amazon alone has well over 2,000 reviews, including hundreds of before/after photos.

Personally, I’ve used Mederma for my chest keloids and have seen slow but steady improvements in scar texture and color (check out my progress photos here).

Mederma has a light texture and mild scent. It’s easy to apply and dries quickly.

Key Features

  • Cepalin (onion extract)
  • Light texture
  • Mild scent
  • Dries quickly

Key Benefits

  • Softens existing scars
  • Reduces scar discoloration
  • Won’t break the bank

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Onion Extract?

Onion extract (allium cepa) has antioxidant and anti-inflammatory properties.

Studies show that onion extract may inhibit fibroblasts (cells that produce collagen). (3) 

This can help soften hypertrophic scars and keloids and may also reduce discoloration. 

Onion extract also contains quercetin, a plant flavonoid that inhibits collagen. (4)

The clinical evidence, however, is still inconclusive:

  • One study reported no difference between onion extract and Vaseline (5)
  • Other studies reported positive results using onion extract (6, 7, 8)
  • One study was funded by Merz (manufacturer of Mederma) (8)

Mederma Reviews

Mederma has well over 2,000 reviews on Amazon. While reviews are mostly positive, Mederma doesn’t work for everyone. 

For some people, Mederma flattened their scars completely. But for others, it didn’t seem to move the needle much.

As with all skincare products, your mileage may vary (YMMV).

Side effects of Mederma may include itchiness, irritation, and redness. 

Read my full review of Mederma here.

Pro Tip: use Mederma 2x daily (instead of 1x) to maintain continuous scar coverage.

The Bottom-Line

Mederma is a popular scar gel that works well and is quite affordable.

Alternatives to Kelo-Cote & Mederma

My Top Pick

My top pick for a silicone gel.

Featuring 100% silicone and vitamin E, NewGel+ is a great balance of effectiveness and affordability (I use it myself).

Budget Pick

An exceptional value silicone gel.

Featuring 100% medical grade silicone, ScarFade is effective for scars while offering amazing value for the money.

For Body Scars

Best for large body scars.

Featuring 100% silicone gel, ScarAway Silicone Scar Sheets is my top pick for large scars from surgery, injury, or burns.

What Causes Scars?

Ever wonder why you get those pesky scars in the first place?

Well, research suggests that genetics are partly to blame (thanks, Mom and Dad). (9)

But scars themselves are a natural response by your body to injuries.

Part 1: Inflammation

When you’re injured, your body sets off an “alarm” signal known as inflammation.

This process jumpstarts the immune system and triggers wound healing signals.

Part 2: Repair

After inflammation comes the repair stage.

Your body replaces damaged skin with new skin cells and materials like collagen.

Collagen fibers weave together to form the foundations of new skin tissue (a “scar”).

Part 3: Scars

Unfortunately, scars are seldom identical to the original skin.

They’re often a different color and may feel hard or lumpy.

Sometimes, scars end up elevated like hypertrophic scars or keloids. 

This happens if your body produced too much collagen during the repair stage.

The Bottom-Line

I hope this guide to Mederma vs Kelo-Cote helps you pick the right product for you. 

Remember, nothing can replace patience and consistency! 

References

  1. Gold MH, et al. International Advisory Panel on Scar Management. “Updated international clinical recommendations on scar management: part 2–algorithms for scar prevention and treatment.” Dermatological Surgery vol. 40,8 (2014): 825-31. https://www.ncbi.nlm.nih.gov/pubmed/25068544
  2. Bleasdale, Benjamin et al. “The Use of Silicone Adhesives for Scar Reduction.” Advances in Wound Care vol. 4,7 (2015): 422-430. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486716/
  3. Cho JW, et al. “Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo.” International Journal of Molecular Medicine vol. 25,3 (2010): 347-52. https://www.ncbi.nlm.nih.gov/pubmed/20127038
  4. Phan TT, et al. “Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars.” Journal of Dermatological Science vol. 33 (2003): 192–4. https://www.ncbi.nlm.nih.gov/pubmed/14643528
  5. Chung VQ, et al. “Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study.” Dermatological Surgery vol. 32,2 (2006): 193-7. https://www.ncbi.nlm.nih.gov/pubmed/16442038
  6. Ho WS, et al. “Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.” Dermatological Surgery vol. 32,7 (2006): 891-6. https://www.ncbi.nlm.nih.gov/pubmed/16875470
  7. Beuth J, et al. “Safety and efficacy of local administration of contractubex to hypertrophic scars in comparison to corticosteroid treatment. Results of a multicenter, comparative epidemiological cohort study in Germany.” In Vivo vol. 20,2 (2006): 277-83. https://www.ncbi.nlm.nih.gov/pubmed/16634531
  8. Draelos, Zoe D et al. “A new proprietary onion extract gel improves the appearance of new scars: a randomized, controlled, blinded-investigator study.” The Journal of Clinical and Aesthetic Dermatology vol. 5,6 (2012): 18-24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390235/
  9. Gauglitz, Gerd G et al. “Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.” Molecular Medicine (Cambridge, Mass.) vol. 17,1-2 (2010): 113-25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978/
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Tom Qiao

I solve skin mysteries using simple science to provide you the best skincare advice!

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