BioCorneum vs Mederma 2019 | What’s Better for Scars?

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Biocorneum vs Mederma

BioCorneum vs Mederma

Preview
Best Overall Results
BioCorneum Advanced Scar Treatment Gel with SPF 30 - Silishield Patented Crosslinking Silicone - 50 gram - Certified Distributor
Best Budget Option
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Product Name
BioCorneum Plus SPF 30 Advanced Scar Treatment
Mederma Advanced Scar Gel
Product Size
50 g
50 g
Recommended for Scars?
Active Ingredients
Polysiloxanes (Silicone), Isopropyl Myristrate, Silicone Dioxide, Chemical Sunscreen
Cepalin® (Onion Extract Gel)
Application Frequency
2x Daily
1x Daily
Customer Rating
Prime Eligibility
Price
$63.97
$28.80
More Information
Best Overall Results
Preview
BioCorneum Advanced Scar Treatment Gel with SPF 30 - Silishield Patented Crosslinking Silicone - 50 gram - Certified Distributor
Product Name
BioCorneum Plus SPF 30 Advanced Scar Treatment
Product Size
50 g
Recommended for Scars?
Active Ingredients
Polysiloxanes (Silicone), Isopropyl Myristrate, Silicone Dioxide, Chemical Sunscreen
Application Frequency
2x Daily
Customer Rating
Prime Eligibility
Price
$63.97
More Information
Best Budget Option
Preview
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Product Name
Mederma Advanced Scar Gel
Product Size
50 g
Recommended for Scars?
Active Ingredients
Cepalin® (Onion Extract Gel)
Application Frequency
1x Daily
Customer Rating
Prime Eligibility
Price
$28.80
More Information

Last Updated: 2020-04-05 / Images from Amazon PA API

Our Recommendations

If you want the best results, go for a silicone gel like BioCorneum.

Silicone gels are recommended by the International Advisory Panel on Scar Management for both hypertrophic scars and keloids. (1)

I like silicone gels because they’re very effective, lightweight, and dry quickly.

On the other hand, if you’re on a limited budget, a good alternative is Mederma.

This popular scar gel can provide you excellent results without breaking the bank.

The downside, however, is that the clinical evidence is not yet conclusive. (1)

RELATED:

BioCorneum Advanced Scar Treatment Plus SPF 30

PROS

  • Reduces scar appearance
  • Alleviates discoloration
  • Includes SPF 30
  • Excellent reviews

CONS

  • Results require patience
  • Expensive

About BioCorneum

BioCorneum is proven to reduce the appearance of both old and new scars. (2)

Featuring patented Silishield™ technology, BioCorneum forms an invisible shield over your scar to create an ideal wound healing environment.

This “second skin” keeps your scar hydrated and normalizes excess collagen formation, which helps prevent new scars and flatten existing ones. (3)

As a nice bonus, BioCorneum also includes SPF 30 to protect scars from sun damage. This is great for scars on the face, hands, and other visible areas of your body.

Key Features

  • Patented Silishield™ technology
  • SPF 30 sun protection
  • Silky smooth texture
  • Invisible and dries quickly

Key Benefits

  • Reduces scar appearance
  • Prevents new scars after surgery
  • Alleviates discoloration (redness)
  • Protects scars from sun damage

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Silicone?

Silicone has been used for scar treatment since the 1980s. (3)

More recently, the International Advisory Panel on Scar Management reiterated the effectiveness of silicone for both hypertrophic scars and keloids. (1)

Researchers believe that silicone works by hydrating and protecting the scar. This prevents skin dehydration which may contribute to abnormal scar formation. (4)

You should apply silicone gels twice a day for at least 2 months.

Why BioCorneum?

According to the company, bioCorneum’s patented Silishield™ crosslinking silicone bonds with skin more effectively than traditional silicone. (5)

That means bioCorneum stays on your skin longer and is less likely to wash off. This is important because silicone gels work best with continuous scar coverage. (4)

In addition, if you’re someone who usually forgets to apply sunscreen, bioCorneum has you covered (quite literally) with SPF 30!

BioCorneum Reviews

Reviews of BioCorneum on Amazon have been very positive. 

Many people bought BioCorneum to minimize scars after surgery at the recommendation of their plastic surgeon.

As with all skincare products, your mileage may vary (YMMV).

Read my full review of BioCorneum here.

The Bottom-Line

BioCorneum is a high quality silicone gel with additional SPF 30 sun protection.

Mederma Advanced Scar Gel

PROS

  • Softens existing scars
  • Reduces discoloration
  • Thousands of reviews
  • Affordable

CONS

  • Inconclusive clinical studies
  • Results require patience
  • May cause itchiness, irritation, or redness

About Mederma

If you want great results that won’t break the bank, Mederma is an excellent option.

Featuring Cepalin (onion extract), Mederma has been the #1 pharmacist recommended brand for 15 years.

Although clinical studies of onion extract are somewhat mixed, it’s clear that Mederma has helped thousands of people with their scar problems.

Amazon alone has well over 2,000 reviews, including hundreds of before/after photos.

Personally, I’ve used Mederma for my chest keloids and have seen slow but steady improvements in scar texture and color (check out my progress photos here).

Mederma has a light texture and mild scent. It’s easy to apply and dries quickly.

Key Features

  • Cepalin (onion extract)
  • Light texture
  • Mild scent
  • Dries quickly

Key Benefits

  • Softens existing scars
  • Reduces scar discoloration
  • Won’t break the bank

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Onion Extract?

Onion extract (allium cepa) has antioxidant and anti-inflammatory properties.

Studies show that onion extract may inhibit fibroblasts (cells that produce collagen). (6) 

This can help soften hypertrophic scars and keloids and may also reduce discoloration. 

Onion extract also contains quercetin, a plant flavonoid that inhibits collagen. (7)

The clinical evidence, however, is still inconclusive:

  • One study reported no difference between onion extract and Vaseline (8)
  • Other studies reported positive results using onion extract (9, 10, 11)
  • One study was funded by Merz (manufacturer of Mederma) (11)

Mederma Reviews

Mederma has well over 2,000 reviews on Amazon. While reviews are mostly positive, Mederma doesn’t work for everyone. 

For some people, Mederma flattened their scars completely. But for others, it didn’t seem to move the needle much.

As with all skincare products, your mileage may vary (YMMV).

Side effects of Mederma may include itchiness, irritation, and redness. 

Read my full review of Mederma here.

Pro Tip: use Mederma 2x daily (instead of 1x) to maintain continuous scar coverage.

The Bottom-Line

Mederma is a popular scar gel that works well and is quite affordable.

Alternatives to BioCorneum & Mederma

My Top Pick

My top pick for a silicone gel.

Featuring 100% silicone and vitamin E, NewGel+ is a great balance of effectiveness and affordability (I use it myself).

Runner-Up

A high quality silicone gel.

Another high quality silicone gel, Kelo-Cote is very effective on hypertrophic scars and keloids but more expensive.

For Body Scars

Best for large body scars.

Featuring 100% silicone gel, ScarAway Silicone Scar Sheets is my top pick for large scars from surgery, injury, or burns.

What Causes Scars?

Ever wonder why you get those pesky scars in the first place?

Well, research suggests that genetics are partly to blame (thanks, Mom and Dad). (3)

But scars themselves are a natural response by your body to injuries.

Part 1: Inflammation

When you’re injured, your body sets off an “alarm” signal known as inflammation.

This process jumpstarts the immune system and triggers wound healing signals.

Part 2: Repair

After inflammation comes the repair stage.

Your body replaces damaged skin with new skin cells and materials like collagen.

Collagen fibers weave together to form the foundations of new skin tissue (a “scar”).

Part 3: Scars

Unfortunately, scars are seldom identical to the original skin.

They’re often a different color and may feel hard or lumpy.

Sometimes, scars end up elevated like hypertrophic scars or keloids. 

This happens if your body produced too much collagen during the repair stage.

The Bottom-Line

I hope this guide to Mederma vs. BioCorneum helps you pick the right product for you. 

Remember, nothing can replace patience and consistency! 

To Recap:

If you want the best results, go for a silicone gel like BioCorneum

If you’re on a limited budget, a good alternative is Mederma.

References

  1. Gold MH, et al. International Advisory Panel on Scar Management. “Updated international clinical recommendations on scar management: part 2–algorithms for scar prevention and treatment.” Dermatological Surgery vol. 40,8 (2014): 825-31. https://www.ncbi.nlm.nih.gov/pubmed/25068544
  2. The Science Behind BioCorneum. Retrieved from https://biocorneum.com/physicians/clinical-data/
  3. Gauglitz, Gerd G et al. “Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.” Molecular Medicine (Cambridge, Mass.) vol. 17,1-2 (2010): 113-25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978/
  4. Bleasdale, Benjamin et al. “The Use of Silicone Adhesives for Scar Reduction.” Advances in Wound Care vol. 4,7 (2015): 422-430. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486716/
  5. BioCorneum Information Pamphlet. Retrieved from http://sientra.com/Content/pdfs/MDC-0197%20R1%20bioCorneum%20Package%20Insert.pdf
  6. Cho JW, et al. “Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo.” International Journal of Molecular Medicine vol. 25,3 (2010): 347-52. https://www.ncbi.nlm.nih.gov/pubmed/20127038
  7. Phan TT, et al. “Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars.” Journal of Dermatological Science vol. 33 (2003): 192–4. https://www.ncbi.nlm.nih.gov/pubmed/14643528
  8. Chung VQ, et al. “Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study.” Dermatological Surgery vol. 32,2 (2006): 193-7. https://www.ncbi.nlm.nih.gov/pubmed/16442038
  9. Ho WS, et al. “Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.” Dermatological Surgery vol. 32,7 (2006): 891-6. https://www.ncbi.nlm.nih.gov/pubmed/16875470
  10. Beuth J, et al. “Safety and efficacy of local administration of contractubex to hypertrophic scars in comparison to corticosteroid treatment. Results of a multicenter, comparative epidemiological cohort study in Germany.” In Vivo vol. 20,2 (2006): 277-83. https://www.ncbi.nlm.nih.gov/pubmed/16634531
  11. Draelos, Zoe D et al. “A new proprietary onion extract gel improves the appearance of new scars: a randomized, controlled, blinded-investigator study.” The Journal of Clinical and Aesthetic Dermatology vol. 5,6 (2012): 18-24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390235/
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Tom Qiao

I solve skin mysteries using simple science to provide you the best skincare advice!

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