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6 Best Vitamin C Serums for Hyperpigmentation of 2025 (Ranked & Reviewed)

Last Update: August 2025
Reviewed By: Tom Qiao

In this article, we've rounded up the best vitamin C serums for hyperpigmentation, including dark spots, melasma, age spots, sun damage, and uneven skin tone.

But that's not all! We explain the science behind each product and why we recommend it so you know what you're getting for your cold hard cash. #SolvingSkinMysteries

👉 TLDR: our top pick is Avène

RELATED ARTICLES:

Best Vitamin C Serum for Hyperpigmentation

  1. Editor's Choice: Avène
  2. Fasted Result Pick: The INKEY List
  3. Best for Sensitive Skin: Cetaphil
  4. #1 Bestseller: numbuzin
  5. Best for Acne Prone Skin: Green Tangerine
  6. Best for Fine Lines: ISDIN
Editor's Choice

Avène Vitamin Activ Cg Radiance Concentrated Serum, 1 fl. oz.

$46.00

Discover radiant, youthful skin with a luxurious concentrate that smooths fine lines, fades dark spots, and boosts glow, all while being gentle and dermatologist tested.

Powered by Vitamin C, Niacinamide, and Bakuchiol to visibly reduce wrinkles, even skin tone, and enhance radiance.

Perfect for anyone seeking brighter, smoother skin and a youthful, glowing complexion.

Brand: Avène
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11/14/2025 09:14 am GMT
Fasted Result Pick

The INKEY List 15% Vitamin C and EGF Serum, 1 fl. oz.

$16.00

Revitalize your skin with a powerful yet gentle formula that brightens, reduces hyperpigmentation, and firms skin for a radiant, youthful glow.

Powered by 15% Ascorbyl Glucoside and plant-based EGF to brighten, regenerate, and improve skin elasticity.

Perfect for all skin types for seeking improves hyperpigmentation, firmer, and rejuvenated skin.

Brand: The INKEY List
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11/14/2025 09:13 am GMT
Best for Sensitive Skin

Cetaphil Vitamin C Serum, 1 fl. oz.

$19.84

Brighten your skincare routine with a gentle yet powerful solution that visibly reduces dark spots and hyperpigmentation while caring for even the most sensitive skin.

Enriched with Vitamin C and Vitamin E, this dermatologist tested serum delivers antioxidant protection and skin brightening benefits.

Perfect for sensitive skin seeking a fragrance free, effective brightening and anti dark spot solution.

Brand: Cetaphil
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11/14/2025 09:03 am GMT
#1 Bestseller

numbuzin No.5 Glutathione Vitamin Concentrated Serum, 1.01 fl. oz.

$26.00 $19.30

Illuminate your skin with a powerhouse Korean skincare solution that targets hyperpigmentation, evens tone, and enhances radiance, all while being gentle enough for sensitive skin.

Formulated with Tranexamic Acid, Niacinamide, Glutathione, and Vitamin C to visibly brighten and reduce dark spots.

Ideal for sensitive skin seeking concentrated care against hyperpigmentation and dullness.

Brand: numbuzin
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11/14/2025 09:04 am GMT
Best for Acne Prone Skin

Green Tangerine Vitamin C Dark Spot Serum

$21.00

Reveal brighter, flawless skin with a potent Korean formula that targets dark spots and post-acne hyperpigmentation while delivering antioxidant-rich nourishment for a radiant glow.

Infused with 70% fresh green tangerine extract, 4% niacinamide, and arbutin to brighten and protect skin.

Ideal for anyone battling dark spots, uneven tone, and post acne marks.

Brand: Green Tangerine
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11/14/2025 09:16 am GMT
Best for Fine Lines

ISDIN Flavo-C Ultraglican Daily Antioxidant Serum (10 Count)

$52.00

Say goodbye to dullness and fine lines with a cutting-edge serum that restores radiance, boosts elasticity, and visibly smooths wrinkles for a youthful, glowing complexion.

Packed with UltraGlycans, Vitamin C, Vitamin E, and Hyaluronic Acid to repair, hydrate, and rejuvenate skin.

Perfect for anyone seeking brighter, firmer skin with reduced wrinkles and fine lines.

Brand: ISDIN
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11/14/2025 09:15 am GMT
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Article written by Tom Qiao
Tom is the founder and editor of TheDermDetective.com where he applies his decades of personal experience with skincare problems like acne and acne scarring to provide readers with practical advice and product recommendations.
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