Natureplex Scar Gel Review 2019 | Better Than Mederma?

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Natureplex Scar Gel Review

If you’re looking for a Natureplex Scar Gel review, you’re in the right place!

I’ve tried dozens of scar products over the years, including onion extract gels like Natureplex.

Essentially, this scar gel uses similar ingredients to Mederma at a fraction of the price.

In terms of scar treatment, clinical studies on onion extract are still inconclusive. (1)

I’ve used Mederma before with good results (see my full review here) but quite frankly I’d recommend that you buy a good quality silicone gel instead.

That’s because silicone is clinically proven to reduce the appearance of scars from surgery (including C-section), accidents, cuts & scrapes, burns, and even acne. (1)

My top recommendation for a silicone gel is NewGel+ (I use it myself). It’s an excellent scar gel with 100% silicone and vitamin E that balances effectiveness and affordability.

Keep reading for my full review of Natureplex!

Natureplex Scar Gel Review

Our Score: 4/5

A super cheap onion extract gel for mild scars (comparable to Mederma).


  • Reduces scar height & size
  • Restores normal skin color
  • Good reviews
  • Super affordable


  • Results require patience
  • Mixed clinical research

To Keep A Long Story Short...

Natureplex Scar Gel is a value brand scar product by DollarTree.

It’s essentially a close duplicate of the more popular Mederma Advanced Scar Gel, which features the key ingredient onion extract.

Clinical research into onion extract is not yet conclusive, which is why I always recommend silicone gels or silicone sheets instead.

Silicone is clinically proven and recommended by the International Advisory Panel on Scar Management for hypertrophic scars and keloids.

My top pick for a silicone gel is NewGel+ (I use it myself).

On the other hand, onion extract gels like Mederma and Natureplex are cheaper because they don’t use medical grade silicone (expensive).

In fact, Natureplex is super cheap (~$6 per oz) compared to Mederma (~$16 per oz) and NewGel+ (~$40 per oz).

So if you want a cheaper alternative to Mederma with similar ingredients, Natureplex is a good option. But if you want the best results for your scars, I recommend using a silicone gel like NewGel+.

What is Natureplex Scar Gel?

Natureplex is an onion extract gel that works on many types of scars, including hypertrophic scars, keloids, surgical scars (such as C-section), and scars from trauma, burns, or injuries.

Key Features

  • Onion extract
  • Allantoin (skin hydrator)
  • Comes in 1.25 oz tube
  • Twice daily application

Key Benefits

  • Flattens raised scars
  • Reduces skin discoloration
  • May prevent scars after surgery
  • Thin, lightweight, easy to apply

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

How Does Natureplex Work?

Onion Extract

Onion extract (allium cepa) has antioxidant and anti-inflammatory properties.

Studies show that onion extract can inhibit fibroblasts (cells that produce collagen). This softens raised scars like hypertrophic scars and keloids and may reduce skin discoloration. (2)  

Onion extract also contains quercetin, a plant flavonoid that inhibits collagen production. (3)

The clinical evidence, however, is not yet conclusive:

  • One study reported no difference between onion extract and Vaseline (4)
  • Other studies reported positive results with onion extract (5, 6, 7)
  • One of these studies was funded by Merz (manufacturer of Mederma) (7)


Allantoin is a natural ingredient found in plants like comfrey, salsify, maple, and wheat germ. 

It promotes the healing process, reduces itching, and softens the scar tissue. 

It’s also an excellent hydrator that helps retain water. This makes the scar look and feel softer.

Natureplex Scar Gel Reviews

Among the positive reviews, people claimed Natureplex reduced the appearance of their scars, including scar size, scar height, and skin redness.

Among the negative reviews, people noted that Natureplex didn’t provide any benefits.

I find that most people don’t use silicone gels long enough to see the desired results. In my experience, it takes between 3-6 months before you’ll notice any significant improvements. 

As with all skincare products, your mileage may vary (YMMV).

"Definitely exceeded my expectations."

I have a keloid from a surgical procedure and my physical therapist recommended Mederma. I know keloids aren't too responsive to treatment and didn't want to waste money. I stumbled upon this cheap cream at dollar tree and been using it frequently just for massage purposes and was pleasantly surprised that within a week I noticed that it appeared smoother and flatter. Good stuff.


"Like Mederma, it uses onion extract as it's key ..."

I purchased this from DollarTree for $1.00, and the gel has a similar texture to Mederma. Like Mederma, it uses onion extract as it's key ingredient. I've been applying it to a new surgical scar on my calf 3 times a day for the past 6 weeks, and the scar has healed considerably during that time. I will continue to use it for the next few months as the directions say to use it for 3 to 6 months.

Mike Ehlert

The Bottom-Line

Natureplex Scar Gel is a super cheap onion extract gel that is similar to Mederma.

It flattens raised scars, reduces skin discoloration, and did I mention the low price?

Due to the mixed clinical research on onion extract, I always recommend silicone gels or silicone sheets for scars. 

My top pick for a silicone gel is NewGel+ (I use it myself).

For large body scars, I recommend a silicone sheet like ScarAway Silicone Scar Sheets.


  1. Gold MH, et al. International Advisory Panel on Scar Management. “Updated international clinical recommendations on scar management: part 2–algorithms for scar prevention and treatment.” Dermatological Surgery vol. 40,8 (2014): 825-31.
  2. Bleasdale, Benjamin et al. “The Use of Silicone Adhesives for Scar Reduction.” Advances in Wound Care vol. 4,7 (2015): 422-430.
  3. Cho JW, et al. “Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo.” International Journal of Molecular Medicine vol. 25,3 (2010): 347-52.
  4. Phan TT, et al. “Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars.” Journal of Dermatological Science vol. 33 (2003): 192–4.
  5. Chung VQ, et al. “Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study.” Dermatological Surgery vol. 32,2 (2006): 193-7.
  6. Ho WS, et al. “Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.” Dermatological Surgery vol. 32,7 (2006): 891-6.
  7. Beuth J, et al. “Safety and efficacy of local administration of contractubex to hypertrophic scars in comparison to corticosteroid treatment. Results of a multicenter, comparative epidemiological cohort study in Germany.” In Vivo vol. 20,2 (2006): 277-83.
  8. Draelos, Zoe D et al. “A new proprietary onion extract gel improves the appearance of new scars: a randomized, controlled, blinded-investigator study.” The Journal of Clinical and Aesthetic Dermatology vol. 5,6 (2012): 18-24.
  9. Gauglitz, Gerd G et al. “Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.” Molecular Medicine (Cambridge, Mass.) vol. 17,1-2 (2010): 113-25.
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Tom Qiao

I solve skin mysteries using simple science to provide you the best skincare advice!

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