iS Clinical vs La Roche-Posay | Which Is Better?

written by: Tom Qiao
last update: February 8, 2024

As a skincare editor who tests an array of serums, I’m often asked how luxury clinical brand iS Clinical compares to leading French pharmacy line La Roche-Posay. While both companies […]

As a skincare editor who tests an array of serums, I’m often asked how luxury clinical brand iS Clinical compares to leading French pharmacy line La Roche-Posay. While both companies formulate advanced treatment serums powered by proven ingredients, they take different approaches. Here’s my take on how these popular serums measure up after trying them myself.

Star Ingredients

The star ingredient in iS Clinical’s Pro-Heal Serum Advance Plus is a botanical antioxidant complex featuring vitamin E, vitamin C and olive leaf extract to target signs of aging. Meanwhile, La Roche-Posay’s Pure Vitamin C Face Serum 10 spotlights a concentrated 10% vitamin C derivative to even skin tone and hydrate while also minimizing fine lines.

Texture and Absorption

Out of the two formulas, iS Clinical’s serum features a luxuriously silky, almost dry oil-esque texture. By contrast, the La Roche-Posay vitamin C serum has a very lightweight, fluid viscosity. Both absorb rapidly without any greasy residue. However, the Pro-Heal Serum leaves skin feeling nourished, whereas the vitamin C has more of a matte finish.

Performance Results

With consistent use, I found both the antioxidant-powered iS Clinical serum and the La Roche-Posay vitamin C treatment make good on their respective claims. The velvety Pro-Heal Serum immediately leaves skin looking plump and renewed while working to even tone over time. However, the pure vitamin C formula fades pigmentation faster while smoothing skin texture.

Suitability for Skin Types

The ultra-silky iS Clinical serum works beautifully for normal, dry and mature skin needing both moisture and antioxidants. For oily or acne-prone complexions, La Roche-Posay’s lightweight vitamin C makes a wiser pick as it won’t feel heavy or pore-clogging while still perfecting and brightening. Both brands suit sensitive skin types.

Reviews and Awards

Devoted fans call the iS Clinical Pro-Heal Serum a “fountain of youth” for instantly renewing lackluster skin while reducing redness and wrinkles long-term. La Roche-Posay’s vitamin C formula also garners praise from customers for fading stubborn sun spots and acne marks without irritation, making sensitive skin happy. Both serums boast skincare awards.

Affordability

Given its clinical-grade formulation, the iS Clinical serum unsurprisingly comes with a hefty $98 price tag for just one fluid ounce. While not cheap, La Roche-Posay still offers an accessible price point under $30 for a full ounce of their medically-proven vitamin C. So it offers brighter skin on a budget!

If you’re seeking serious anti-aging ability paired with instant rejuvenation, the iS Clinical Pro-Heal Serum makes a luxuriously potent choice. For those aiming to even skin tone and texture without breakouts or redness, La Roche-Posay’s pure Vitamin C offers elegant efficacy affordably. Both are true skin-perfecting gems!

Article written by Tom Qiao

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