Derma E Scar Gel vs Mederma 2019 | What’s Better for Scars?

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Derma E Scar Gel vs Mederma

Derma E Scar Gel vs Mederma

Preview
Best Budget Option
DERMA E Scar Gel, Helps Scarred Skin Heal, 2 oz
Best Value for Money
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Best Overall Results
NewGel+ Advanced Silicone Gel for Scars, 1 Ounce
Product Name
Derma E Scar Gel
Mederma Advanced Scar Gel
NewGel+ Advanced Silicone Gel for Scars
Product Size
56 g
50 g
30 g
Recommended for Scars?
Active Ingredients
Allium Cepa (Onion Extract), Panthenol, Allantoin
Cepalin® (Onion Extract), Panthenol, Allantoin
Polysiloxanes (Silicone Gel), Vitamin E
Application Frequency
2x Daily
1x Daily
2x Daily
Customer Rating
Prime Eligibility
Price
$15.75
$28.80
$54.00
Best Budget Option
Preview
DERMA E Scar Gel, Helps Scarred Skin Heal, 2 oz
Product Name
Derma E Scar Gel
Product Size
56 g
Recommended for Scars?
Active Ingredients
Allium Cepa (Onion Extract), Panthenol, Allantoin
Application Frequency
2x Daily
Customer Rating
Prime Eligibility
Price
$15.75
More Information
Best Value for Money
Preview
Mederma Advanced Scar Gel - 1x Daily - Reduces The Appearance of Old & New Scars - #1 Doctor & Pharmacist Recommended Brand for Scars - 1.76oz.
Product Name
Mederma Advanced Scar Gel
Product Size
50 g
Recommended for Scars?
Active Ingredients
Cepalin® (Onion Extract), Panthenol, Allantoin
Application Frequency
1x Daily
Customer Rating
Prime Eligibility
Price
$28.80
More Information
Best Overall Results
Preview
NewGel+ Advanced Silicone Gel for Scars, 1 Ounce
Product Name
NewGel+ Advanced Silicone Gel for Scars
Product Size
30 g
Recommended for Scars?
Active Ingredients
Polysiloxanes (Silicone Gel), Vitamin E
Application Frequency
2x Daily
Customer Rating
Prime Eligibility
Price
$54.00
More Information

Last Updated: 2020-04-05 / Images from Amazon PA API

Our Recommendations

Derma E Scar Gel is a good alternative to Mederma that uses the same key ingredient, onion extract. The clinical research on onion extract, however, is not yet conclusive. (1)

For best results, I recommend trying a silicone gel instead like NewGel+.

Silicone gels are recommended by the International Advisory Panel on Scar Management for both hypertrophic scars and keloids. (1)

I also like silicone gels because they’re effective, lightweight, and dry quickly.

I’ve had success with Mederma in the past for my chest keloids (see here) but found that side effects include itchiness and discoloration (skin darkening), which don’t occur with silicone gels.

Finally, Derma E Scar Gel is more affordable and comes in a 2 oz tub format. It also includes panthenol and glycerin for additional skin hydration.

RELATED:

Derma E Scar Gel

PROS

  • Reduces scar height & size
  • Restores normal skin color
  • Panthenol (hydrating)
  • Excellent reviews
  • Super affordable

CONS

  • Results require patience
  • Mixed clinical research

Derma E Scar Gel is an onion extract based gel that works on hypertrophic scars, keloids, surgical scars (such as C-section), and scars from trauma, burns, or injuries.

Key Features

  • Onion extract (same as Mederma)
  • Panthenol (deep hydration)
  • Glycerin (hydration)
  • Comes in 2.0 oz tub
  • Requires 2-3x daily application

Key Benefits

  • Flattens raised scars
  • Reduces skin discoloration
  • Helps prevent scars after surgery
  • Thin, lightweight, easy to apply
  • Affordable

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Onion Extract?

Onion extract (allium cepa) has antioxidant and anti-inflammatory properties.

Studies show that onion extract can inhibit fibroblasts (cells that produce collagen). This softens raised scars like hypertrophic scars and keloids and may reduce skin discoloration. (2)  

Onion extract also contains quercetin, a plant flavonoid that inhibits collagen production. (3)

The clinical evidence, however, is not yet conclusive:

  • One study reported no difference between onion extract and Vaseline (4)
  • Other studies reported positive results with onion extract (5, 67)
  • One of these studies was funded by Merz (manufacturer of Mederma) (7)

Derma E Scar Gel Reviews

Reviews of Derma E Scar Gel on Amazon are mainly positive. Many reviewers noticed improvements in post-surgical scars, hypertrophic scars, and keloids.

Among the negative reviews, some people felt that Derma E Scar Gel didn’t deliver any better results than Vaseline or Mederma.

As with all skincare products, your mileage may vary (YMMV).

The Bottom-Line

Derma E Scar Gel is an effective scar product that uses onion extract (same as Mederma).

Mederma Advanced Scar Gel

PROS

  • Softens existing scars
  • Reduces discoloration
  • Thousands of reviews
  • Affordable

CONS

  • Inconclusive clinical studies
  • Results require patience
  • May cause itchiness, irritation, or redness

About Mederma

If you want great results that won’t break the bank, Mederma is an excellent option.

Featuring Cepalin (onion extract), Mederma has been the #1 pharmacist recommended brand for 15 years.

Although clinical studies of onion extract are somewhat mixed, it’s clear that Mederma has helped thousands of people with their scar problems.

Amazon alone has well over 2,000 reviews, including hundreds of before/after photos.

Personally, I’ve used Mederma for my chest keloids and have seen slow but steady improvements in scar texture and color (check out my progress photos here).

Mederma has a light texture and mild scent. It’s easy to apply and dries quickly.

Key Features

  • Cepalin (onion extract)
  • Light texture
  • Mild scent
  • Dries quickly

Key Benefits

  • Softens existing scars
  • Reduces scar discoloration
  • Won’t break the bank

Suitable For

  • Hypertrophic scars
  • Keloids (including on the chest or earlobes)
  • Surgical scars (including C-section)
  • Scars from trauma, burns, or injuries
  • Scars on the face, hands, and other visible areas

Why Onion Extract?

Onion extract (allium cepa) has antioxidant and anti-inflammatory properties.

Studies show that onion extract may inhibit fibroblasts (cells that produce collagen). (3) 

This can help soften hypertrophic scars and keloids and may also reduce discoloration. 

Onion extract also contains quercetin, a plant flavonoid that inhibits collagen. (4)

The clinical evidence, however, is still inconclusive:

  • One study reported no difference between onion extract and Vaseline (5)
  • Other studies reported positive results using onion extract (6, 7, 8)
  • One study was funded by Merz (manufacturer of Mederma) (8)

Why Mederma?

In my opinion, the main selling point of Mederma is the price.

It’s more affordable than alternative scar treatments like silicone gels and corticosteroid injections, both of which are used for hypertrophic scars and keloids. 

Mederma is also widely available at retailers like Wal-Mart and online at Amazon.

As for the product itself, it definitely works (see my progress photos here). 

But it requires a lot of patience and most people quit too early. In my experience, it takes at least 3 months before you’ll see any noticeable results.

Mederma Reviews

Mederma has well over 2,000 reviews on Amazon. While reviews are mostly positive, Mederma doesn’t work for everyone. 

For some people, Mederma flattened their scars completely. But for others, it didn’t seem to move the needle much.

As with all skincare products, your mileage may vary (YMMV).

Side effects of Mederma may include itchiness, irritation, and redness. 

Read my full review of Mederma here.

Pro Tip: use Mederma 2x daily (instead of 1x) to maintain continuous scar coverage.

The Bottom-Line

Mederma is a popular scar gel that works well and is quite affordable.

Alternatives to Derma E Scar Gel & Mederma

My Top Pick

My top pick for a silicone gel.

Featuring 100% silicone and vitamin E, NewGel+ boasts amazing reviews on Amazon at a very affordable price.

Runner-Up

A high quality silicone gel.

Another high quality silicone gel, Kelo-Cote is very effective on hypertrophic scars and keloids but more expensive.

For Body Scars

Best for large body scars.

Featuring medical grade silicone, ScarAway is my top pick for larger scars from surgery, injury, or burns.

What Causes Scars?

Ever wonder why you get those pesky scars in the first place?

Well, research suggests that genetics are partly to blame (thanks, Mom and Dad). (9)

But scars themselves are a natural response by your body to injuries.

Part 1: Inflammation

When you’re injured, your body sets off an “alarm” signal known as inflammation.

This process jumpstarts the immune system and triggers wound healing signals.

Part 2: Repair

After inflammation comes the repair stage.

Your body replaces damaged skin with new skin cells and materials like collagen.

Collagen fibers weave together to form the foundations of new skin tissue (a “scar”).

Part 3: Scars

Unfortunately, scars are seldom identical to the original skin.

They’re often a different color and may feel hard or lumpy.

Sometimes, scars end up elevated like hypertrophic scars or keloids. 

This happens if your body produced too much collagen during the repair stage.

The Bottom-Line

I hope this guide to Mederma vs. Derma E Scar Gel helps you pick the right product for you. 

Remember, nothing can replace patience and consistency! 

To Recap:

If you want the best results, go for a silicone gel like NewGel+

If you’re on a limited budget, a good alternative is Derma E Scar Gel or Mederma.

References

  1. Gold MH, et al. International Advisory Panel on Scar Management. “Updated international clinical recommendations on scar management: part 2–algorithms for scar prevention and treatment.” Dermatological Surgery vol. 40,8 (2014): 825-31. https://www.ncbi.nlm.nih.gov/pubmed/25068544
  2. Bleasdale, Benjamin et al. “The Use of Silicone Adhesives for Scar Reduction.” Advances in Wound Care vol. 4,7 (2015): 422-430. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4486716/
  3. Cho JW, et al. “Onion extract and quercetin induce matrix metalloproteinase-1 in vitro and in vivo.” International Journal of Molecular Medicine vol. 25,3 (2010): 347-52. https://www.ncbi.nlm.nih.gov/pubmed/20127038
  4. Phan TT, et al. “Quercetin inhibits fibronectin production by keloid-derived fibroblasts. Implication for the treatment of excessive scars.” Journal of Dermatological Science vol. 33 (2003): 192–4. https://www.ncbi.nlm.nih.gov/pubmed/14643528
  5. Chung VQ, et al. “Onion extract gel versus petrolatum emollient on new surgical scars: prospective double-blinded study.” Dermatological Surgery vol. 32,2 (2006): 193-7. https://www.ncbi.nlm.nih.gov/pubmed/16442038
  6. Ho WS, et al. “Use of onion extract, heparin, allantoin gel in prevention of scarring in chinese patients having laser removal of tattoos: a prospective randomized controlled trial.” Dermatological Surgery vol. 32,7 (2006): 891-6. https://www.ncbi.nlm.nih.gov/pubmed/16875470
  7. Beuth J, et al. “Safety and efficacy of local administration of contractubex to hypertrophic scars in comparison to corticosteroid treatment. Results of a multicenter, comparative epidemiological cohort study in Germany.” In Vivo vol. 20,2 (2006): 277-83. https://www.ncbi.nlm.nih.gov/pubmed/16634531
  8. Draelos, Zoe D et al. “A new proprietary onion extract gel improves the appearance of new scars: a randomized, controlled, blinded-investigator study.” The Journal of Clinical and Aesthetic Dermatology vol. 5,6 (2012): 18-24. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3390235/
  9. Gauglitz, Gerd G et al. “Hypertrophic scarring and keloids: pathomechanisms and current and emerging treatment strategies.” Molecular Medicine (Cambridge, Mass.) vol. 17,1-2 (2010): 113-25. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022978/
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Tom Qiao

I solve skin mysteries using simple science to provide you the best skincare advice!

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